Chitinase-like protein 1

Author: msrf

August undefined, 2024

WebChitinase-3-like protein 1 (CHI3L1) is a secreted glycoprotein characterized by its ability to regulate multiple biological processes, such as the inflammatory response and gene transcriptional signaling activation. Abnormal CHI3L1 expression has been associated with multiple neurological disorders and serves as a biomarker for the early ... WebBecause of their amino acid sequence similarities, human chitinases are classified into the 18 glycosyl hydrolase (GH18) family. 2, –, 4 The human protein family encodes 2 true chitinases, chitotriosidase (CHIT1), and acidic mammalian chitinase (AMCase), and several CLPs: chitinase-3-like 1 (CHI3L1), chitinase-3-like 2 (CHI3L2), oviductin ...

Diagnosis of cardiac surgery-associated acute kidney …

WebFeb 14, 2024 · NM_001374626.1 → NP_001361555.1 chitinase-3-like protein 1 isoform 2 precursor. Status: VALIDATED. Source sequence(s) AC137104 Consensus CDS CCDS87878.1 Related ENSMUSP00000119205.2, ENSMUST00000156873.8 Conserved Domains (1) summary cd02872 Location: 22 → 378 WebJun 9, 2024 · YKL-40 (also named Chitinase-3-like I) has been frequently investigated in body fluids as a surrogate marker of neuroinflammation in AD and other neurological disorders. However, the expression pattern of YKL-40 in the human brain with neurodegenerative pathology remains poorly investigated. greenway motors il

Chitinases and Chitinase-Like Proteins in Obstructive Lung …

WebChitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N … WebObjective: To evaluate the classifier performance, clinical and biochemical correlations of cerebrospinal fluid (CSF) levels of the chitinase proteins Chitotriosidase-1 (CHIT1), Chitinase-3-like protein 1 (CHI3L1) and Chitinase-3-like protein 2 (CHI3L2) in amyotrophic lateral sclerosis (ALS). Methods: CSF levels of CHIT1, CHI3L1, CHI3L2, … WebFeb 19, 2024 · Systemic sclerosis (SSc) is an autoimmune disease with completely undefined etiology and treatment difficulties. The expression of both protein coding and … greenway motel redmond or

IJMS Free Full-Text Acidic Chitinase-Chitin Complex Is …

CHI3L1 - Wikipedia

WebApr 6, 2024 · IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown. Some studies have identified chitinase-3 like-protein-1 (YKL-40) and matrix metalloproteinase (MMP)-9 as circulating inflammatory factors involved in positive vascular remodelling. Herein, we … greenway mortgage funding corpWebThe Quantikine Human CHI3L1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure CHI3L1 in cell culture supernates, serum, plasma, and urine. It contains NS0 … greenway motors

"WebJan 25, 2024 · Acidic chitinase (Chia) has been implicated in asthma, allergic inflammations, and food processing. We have purified Chia enzymes with striking acid stability and protease resistance from chicken and pig stomach tissues using a chitin column and 8 M urea (urea-Chia). Here, we report that acetic acid is a suitable agent for native … " - Chitinase-like protein 1

Chitinase-like protein 1

Biomedicines Free Full-Text The lncRNAs/miR-30e/CHI3L1 Axis …

WebThe human homologue chitinase 3-like protein 1 was found to be more excreted in urine from septic patients with AKI than without. In summary, urinary chitinase 3-like protein 1 and -3 and acidic mammalian chitinase discriminated sepsis from sepsis-induced AKI in mice. Further studies of human chitinase proteins are likely to lead to additional ... WebFollowing re-crystallization at neutral pH, the crystals were identified as the chitinase-like protein Ym1, expressed in organs of the lymphoreticular system, the lung, and distal stomach . Co-expression of Ym1 with Mac-1 and scavenger receptor pinpoints macrophages as its main producer .

Did you know?

WebBackground: Chitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also called YKL-40 or human cartilage glycoprotein 39 (HCGP39), is a 39 kDa glycoprotein member of the glycosyl … WebChitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein member of the glycoside hydrolase 18 chitinase family that targets chitin …

WebApr 4, 2024 · CHI3L1, chitinase 3 like 1 Vertebrate Orthologs 2 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog ... PR:000005423 chitinase-3 … WebChitinase 3-like 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation, macrophage polarization, apoptosis, and carcinogenesis. The expression of CHI3L1 is strongly increased by various inflammatory and immunological conditions, including rheumatoid arthritis, multiple sclerosis, Alzheimer's disease, and several cancers.

WebJan 25, 2024 · Acidic chitinase (Chia) has been implicated in asthma, allergic inflammations, and food processing. We have purified Chia enzymes with striking acid … WebChitinase-3-Like Protein 1. YKL-40, a 40 kDa plasma protein, is the best-known protein from the CLPs group. YKL-40 lacks chitinolytic activity due to the mutation of glutamic acid to leucine in the chitinase-3-like catalytic domain. 27 The expression of YKL-40 was found in different mammalian organs and tissues (ie, ...

WebJohansen and Carretta et al. found that COS exerted their anti-tumorigenic effects through the inhibition of YKL-40 (also known as chitinase-3-like 1 or Chi3L1), which is a conserved, secreted chitinase-like protein (CLP) found in elevated levels in many diseases, including cancer [126,127].

WebMar 12, 2024 · Chitinase-3-like Protein 1 Is Associated with Poor Virologic Control and Immune Activation in Children Living with HIV. Bernard I, et al. Viruses, 2024 Nov 23. … greenway mortgage fundingWebMar 21, 2024 · CHIT1 (Chitinase 1) is a Protein Coding gene. Diseases associated with CHIT1 include Chitotriosidase Deficiency and Gaucher's Disease.Among its related pathways are Digestion and absorption and Innate Immune System.Gene Ontology (GO) annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl … fnrs f1 proefWebAug 16, 2024 · Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma. J Clin Invest. 2024 Aug 16;131 (16):e147552. doi: 10.1172/JCI147552. greenway motel redmond oregonWebBackground and Objectives Multiple sclerosis (MS) is an autoimmune disease confined in the CNS, and its course is frequently subtle and variable. Therefore, predictive biomarkers are needed. In this scenario, we conducted a systematic review and meta-analysis to evaluate the reliability of chitinase 3–like 1 as a biomarker of MS. Methods Research … fnrs f8WebMar 28, 2024 · chitinase-3-like protein 1, CGP-39, GP-39, YKL-40, breast regression protein 39, cartilage glycoprotein 39, chitinase 3-like 1. GeneRIFs: Gene References Into Functions. Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer. greenway motors chryslerWebApr 6, 2024 · IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown. Some studies … fnrs f9WebFeb 19, 2024 · Systemic sclerosis (SSc) is an autoimmune disease with completely undefined etiology and treatment difficulties. The expression of both protein coding and non-coding RNAs is dysregulated during disease development. We aimed to examine a possible regulatory axis implemented in the control of chitinase-3 like protein 1 … fnrs focal point