WebSep 27, 2004 · Function. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. WebMar 7, 2002 · The interactions of three subunits of cytoplasmic dynein from Drosophila melanogaster, LC8, Tctex-1, and the N-terminal domain of IC74 (N-IC74, residues 1−289), were characterized in vitro by affinity methods, limited proteolysis, and circular dichroism spectroscopy. These subunits were chosen for study because they are presumed to …
rsph10b2 related genes - GeneCards Search Results
WebJul 1, 2024 · Objective: To investigate dynein light chain Tctex-type 3 (DYNLT3) protein expression in ovarian epithelial lesions and explore the effects and related mechanisms of DYNLT3 in terms of the biological behavior of ovarian cancer. Materials and methods: Initially, expression of the DYNLT3 protein in ovarian epithelial lesions was detected by … WebJun 20, 2006 · In this study, by using a combination of in situ hybridization, bromodeoxyuridine incorporation, immunocolocalization, and ultrastructural studies, we show that in rodents Tctex-1, a cytoplasmic dynein light chain, is selectively enriched in almost all cycling progenitors and young neuronal progeny, but not in mature granular … dewalt corporation headquarters
DYNLT2B - Dynein light chain Tctex-type protein 2B - Function
WebMay 20, 2024 · The cytoplasmic dynein 1 motor (referred to henceforth as dynein) is primarily responsible for microtubule minus-end-directed cargo transport in the cytoplasm … WebA dynein light chain of sea urchin sperm flagella is a homolog of mouse Tctex 1, which is encoded by a gene of the t complex sterility locus [1]. The chromosomal location and pattern of expression of tctex-1 make it a candidate for involvement in male sterility [2]. Expression of tctex-1 mRNA and protein was observed in all lymphoma lines ... WebApr 30, 2015 · For example, the LC8 family members of dynein light chains have been shown to interact, besides dynein, with a large number of proteins. 18 Similarly, the Tctex family member of Tctex-1 (or DYNLT1) has dynein-independent roles in actin remodeling during neurite outgrowth 19 and in ciliary resorption. 20,21 We now show that Tctex-1 … dewalt corporate office