Sec61 antibody

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August undefined, 2024

Web15 May 1999 · The heteromeric Sec61 complex is composed of (alpha), beta and (gamma) subunits and forms the core of the mammalian ER translocon. Oligomers of the Sec61 … WebSee all SEC61B primary antibodies Description Rabbit polyclonal to SEC61B Host species Rabbit Specificity Ab15576 detects human, dog, pig, and rat sec61 beta from microsomes and shows no cross-reactivity with other …

SEC62 Antibodies

Web11 Jan 2024 · Sec61α is a mycolactone-sensitive Sec61 client that was mildly upregulated by mycolactone in previous proteomic studies using various cancer cell lines (Grotzke et … Web15 Jun 2024 · Abstract. KZR-261 is a first-in-class small molecule Sec61 inhibitor currently in a Phase I clinical trial in patients with advanced solid tumors (NCT05047536). We … speed devils dreamcast

Sec61α Antibody (G-2) SCBT - Santa Cruz Biotechnology

Web6 Oct 2024 · The heterotrimeric Sec61 protein complex forms the functional core of the so-called translocon that forms an aqueous channel in the endoplasmic reticulum (ER). The … WebAnti-Sec61 beta Antibody (E-6) is recommended for detection of Sec61β of mouse, rat and human origin by WB, IP, IF, IHC (P) and ELISA Anti-Sec61 beta Antibody (E-6) is available conjugated to agarose for IP; HRP for WB, IHC (P) and ELISA; and to either phycoerythrin or FITC for IF, IHC (P) and FCM Web25 May 2024 · In the syngeneic MC38 model, administration of KZR-834 in combination with anti-PD1 antibody resulted in greater anti-tumor activity than either single agent. Conclusions: Novel Sec61 inhibitors potently block expression of secreted and membrane proteins, translating into anti-tumor activity against many tumor types in vitro and in vivo, … speed devils dreamcast review

Preclinical evaluation of KZR-261, a novel small molecule inhibitor …

Anti-SEC61 Antibody Products from Proteintech Group Inc

WebSEC61 alpha Antibodies Antibodies that detect SEC61 alpha can be used in several scientific applications, including Western Blot and Immunocytochemistry. These antibodies target SEC61 alpha in Mouse, Human and Rat samples. Our SEC61 alpha polyclonal and recombinant monoclonal antibodies are developed in Rabbit. WebSEC61 antibody LS-C185813 is an unconjugated rabbit polyclonal antibody to SEC61 (SEC61A1) (aa413-476) from human. It is reactive with human, mouse, rat and other … speed development in business studiesWeb18 May 1998 · The Sec61 complex represents the essential core of the translocation machinery in the ER membrane. It consists of three subunits, an α subunit (Sec61α) that spans the membrane 10 times, and β and γ subunits (Sec61β and Sec61γ, respectively) that each span the membrane a single time. speed development training

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Sec61 antibody

The Translocon Protein Sec61 Mediates Antigen Transport

Web19 May 2015 · Immunoblot analysis using a Sec61-specific antibody revealed that this band indeed corresponded to Sec61α (Figure 5 D). Additionally, the expression of his-tagged … WebSec61, termed SecYEG in prokaryotes, is a membrane protein complex found in all domains of life. As the core component of the translocon, it transports proteins to the endoplasmic …

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WebSEC61A1 Antibodies (Sec61 alpha 1 Subunit (SEC61A1)) The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion … Web21 Mar 2024 · SEC61B (SEC61 Translocon Subunit Beta) is a Protein Coding gene. Diseases associated with SEC61B include Polycystic Liver Disease and Liver Disease . Among its …

Web19 May 2015 · Sec61 is recruited toward antigen-containing endosomes • An ER-retained intrabody to prevent Sec61 transport from the ER toward endosomes • Endosomal Sec61 is required for antigen translocation and cross-presentation • Recruitment of Sec61 toward antigen-containing endosomes via TRIF signaling Summary WebAnti-SEC61 Antibody Products. Anti-SEC61 antibodies can be readily obtained from commercial sources. The SEC61 protein is a reported synonym for the human gene …

WebImmunocytochemistry/ Immunofluorescence: SEC61B Antibody [NBP2-93984] - Analysis of L929 cells using SEC61B at dilution of 1:100. Blue: DAPI for nuclear staining. Genetic Strategies: Knockout Validated: SEC61B Antibody [NBP2-93984] - Analysis of extracts from normal (control) and SEC61B knockout (KO) 293T cells, using SEC61B at 1:1000 dilution ... WebA rabbit polyclonal antibody, raised against Protein transport protein Sec61 subunit alpha isoform 1 (Human), supplied by Abcam. Menu Sign in or Register Search; Custom …

WebOur SEC61A Antibodies can be used in a variety of model species: Canine, Human, Mouse, Porcine, Rat. Use the list below to choose the SEC61A Antibody which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and related products. Choose from our SEC61A polyclonal antibodies.

WebThe heteromeric SEC61 complex is composed of alpha, beta and gamma subunits. Oligomers of the SEC61 complex form a transmembrane channel where proteins are … speed dial 2 for microsoft edgeWeb29 Apr 2024 · Plasmid mCherry-Sec61β from Dr. Stephen Royle's lab contains the insert Protein transport protein Sec61 subunit beta and is published in J Cell Biol. 2024 Jun … speed dial 2 new tab edgeWeb1 Jul 2024 · The heterotrimeric Sec61 complex (α, β, γ subunits) forms a protein-conducting aqueous channel through which polypeptides are translocated into and across the ER … speed dial 3d for edgeWeb24 Apr 2024 · The Sec61 channel is also a candidate for the dislocation channel for misfolded proteins from the ER to the cytosol during ER-associated degradation (ERAD). … speed dial app for edgeWebCompare Anti-SEC61 Western Blot Antibody Products from leading suppliers on Biocompare. View specifications, prices, citations, reviews, and more. speed dial 4 record formsWebOur SEC61A Antibodies can be used in a variety of model species: Canine, Human, Mouse, Porcine, Rat. Use the list below to choose the SEC61A Antibody which is most appropriate … speed dial android appWeb24 Apr 2024 · The Sec61 channel is also a candidate for the dislocation channel for misfolded proteins from the ER to the cytosol during ER-associated degradation (ERAD). The structure of the Sec61 complex is highly conserved, but the roles of its N-terminal acetylation and its amphipathic N-terminal helix are unknown so far. ... Antibodies against … speed dial att cingular flip 4