WebDec 1, 2024 · Extraction and isolation The culture was filtered and the filtrate was extracted four times with the same volume of ethyl acetate (EtOAc). The organic phase was collected and concentrated under reduced pressure at 38 °C. WebSenegenin (Sen), the major and most effective ingredient of Radix Polygalae, which has anti-apoptotic and anti-oxidative effects. The aim of this study was to investigate the anti-apoptotic and anti-oxidant effects of Sen on Aβ 1-42 -induced PC12 cells apoptosis and oxidative stress as well as its possible signaling pathway.
Neuroprotective Effects and Mechanisms of Senegenin, an …
WebNov 13, 2013 · The method was applied to the pharmacokinetics studies of polygala acid, senegenin and DSS. The analysis was carried out on an Agilent Eclipse plus C 18 … WebApr 1, 2014 · Senegenin, an active component of extracts from Polygala tenuifolia root, a traditional Chinese medicine, has neuroprotective and neuroregenerative effects. However, the mechanism underlying the... slab box ideas ceramics
Simultaneous analysis of polygala acid, senegenin and 3,6 ...
WebJan 23, 2016 · Senegenin, a principle saponin of Polygala tenuifolia Willd., which has empirically shown to improve cognition and intelligence, was chosen to evaluate its cytoprotective potential and possible neuritogenic and neuroprotective effects. WebProtective effect of senegenin on splenectomy-induced postoperative cognitive dysfunction in elderly rats Exp Ther Med. 2014 Apr;7 (4):821-826. doi: 10.3892/etm.2014.1501. Epub 2014 Jan 24. Authors Luyuan Yu 1 , Lei Sun 2 , Suli Chen 3 Affiliations 1 Department of Anesthesiology, Haidian Hospital, Haidian, Beijing 100080, … WebJan 24, 2014 · Senegenin, an active component of extracts from Polygala tenuifolia root, a traditional Chinese medicine, has neuroprotective and neuroregenerative effects. However, the mechanism underlying the effects of senegenin against postoperative cognitive impairment in elderly individuals has yet to be elucidated. ... RNA extraction and … slab boys film