WebApr 10, 2024 · Anzai F, Karasawa T, Komada T, Yamada N, Miura Y, Sampilvanjil A, et al. Calciprotein Particles Induce IL-1β/α-Mediated Inflammation through NLRP3 … WebStefanie Luecke, Søren R. Paludan, in Advances in Virus Research, 2015. 2.4 AIM2. Transfected DNA of bacterial, viral, and mammalian origin causes formation of the …
Increased Mature Interleukin-1β (IL-1β) Secretion from …
WebAug 19, 2016 · Caspase-1 activation and IL-1β production from THP-1 cells by Western blotting and the culture supernatant by enzyme-linked immunosorbent assay analysis … Web1.1 材料 人单核细胞(THP-1细胞)购自美国ATCC;DMSO培养基、佛波酯(PMA)购自美国 Sigma公司;FBS、EDTA购自美国Gibcog公司;吡格列酮(Piog,PPAR-γ激动剂) … afpp annual conference
Blocking the CXCL1-CXCR2 axis enhances the effects of …
WebMar 27, 2024 · On the one hand, the activation of Nod-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome requires nuclear factor kappa B (NF-κB)-dependent … To further investigate whether RIG-I can affect EV-A71-induced IL-1β release in an NLRP3-independent manner, NLRP3 KD THP-1 macrophages were transfected with siRIG-I and then infected with EV-A71. The expression levels of RIG-I, NLRP3, and EV-A71 VP0 were confirmed by Western blotting (Fig. 3A). The … See more TLRs are known to be implicated in pathogen-induced IL-1β production31. Among these TLRs, evidence suggests that TLR3 and TLR8 play roles in RNA virus … See more TLR engagement has been demonstrated to be sufficient to promote inflammasome activation in human monocytes. To test the effects of TLR3 and TLR8 … See more To determine the potential of viral RNAs in triggering IL-1β release, different amounts of EV-A71 vRNA were transfected into THP-1 macrophages. The expression … See more WebMar 30, 2016 · To ensure the effects of ADAM10 inhibition on ADAM10 cell surface expression and Hla-induced IL-1β was not limited to THP1 cells, we tested whether … afp parametr